SLC39A12

Across TCGA patient cohorts, SLC39A12 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A12-associated genes across cancer lineages are FASN, TFRC, and 14-3-3_beta. Each is linked with SLC39A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A12-to-partner and partner-to-SLC39A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SLC39A12-low versus SLC39A12-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A12→partner) and Y-score (partner→SLC39A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	FASN →	+0.634	+2.823	.003	.034	3	3
UCEC	TFRC →	+0.542	+2.115	.004	.017	3	3
LUAD	14-3-3_beta →	-0.095	-1.720	.033	.006	3	2
LUAD	FoxM1 →	+0.240	+1.820	.004	.014	3	2
LUAD	MSH6 →	+0.254	+2.347	.009	.002	3	2
LUAD	S6 →	+0.242	+1.474	.008	.014	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

FASN by SLC39A12 expression — STAD

Explore this box plot interactively →