SLC39A12

Across TCGA cell cohorts, SLC39A12 RNA expression is significantly associated with the go_rna of many other GO terms, with 390 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC39A12-associated GO terms across cancer lineages are Regulation of protein polyubiquitination, Cellular response to glucose starvation, and B cell homeostasis. Each is linked with SLC39A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A12-to-partner and partner-to-SLC39A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein polyubiquitination grouped by SLC39A12-low versus SLC39A12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A12→partner) and Y-score (partner→SLC39A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein polyubiquitination →	+0.057	+0.044	.008	.009	3	3
BREAST	Cellular response to glucose starvation →	+0.059	+0.042	<.001	.007	3	3
BLOOD_Leukemia	B cell homeostasis →	+0.073	+0.040	.009	.006	3	3
BLOOD_Leukemia	Regulation of leukocyte chemotaxis →	+0.048	+0.040	.008	.006	3	3
BLOOD_Leukemia	Regulation of sensory perception of pain →	+0.123	+0.039	<.001	.008	3	3
BLOOD_Leukemia	Regulation of sensory perception →	+0.123	+0.039	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

Regulation of protein polyubiquitination by SLC39A12 expression — BREAST

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