SLC39A11

Across TCGA pan-cancer cohorts, SLC39A11 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC39A11 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC39A11 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated SLC39A11 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and STAD are the cancer types where SLC39A11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.654	.028	16	view →
STAD	OS	Median	III,IV	0.003	0.630	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC39A11–UCEC (OS)

Open the UCEC breakdown →