SLC39A11

Across TCGA pan-cancer cohorts, SLC39A11 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC39A11 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC39A11 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC39A11 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where SLC39A11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.600	0.987	.003	35	view →
PDAC	DFS	Quartile	III,IV	0.431	0.960	.022	6	view →
GBM	OS	Median	All	0.618	0.429	.019	4	view →
LUAD	OS	Median	III,IV	0.861	0.384	.030	2	view →
LSCC	DFS	Quartile	II,III,IV	0.187	0.766	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC39A11–CCRCC (OS)

Open the CCRCC breakdown →