SLC39A11

Across TCGA patient cohorts, SLC39A11 mutation is significantly associated with the RNA expression of many other genes, with 2,397 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A11-associated genes across cancer lineages are RNU5E-9P, PDE4DIPP3, and OR5H5P. Each is linked with SLC39A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A11-to-partner and partner-to-SLC39A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by SLC39A11-low versus SLC39A11-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A11→partner) and Y-score (partner→SLC39A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU5E-9P →	+0.251	+5.087	<.001	.002	3	2
COAD	PDE4DIPP3 →	+0.033	+3.271	.008	.009	3	2
STAD	OR5H5P →	+0.155	+5.070	<.001	.004	3	2
CESC	MIR7-3 →	+0.370	+6.342	<.001	.001	3	2
CESC	DNMT3AP1 →	+0.030	+5.418	<.001	.005	3	2
UCEC	HIRA →	+0.479	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,397 associations by consensus.

RNU5E-9P by SLC39A11 expression — COAD

Explore this box plot interactively →