SLC39A11

Across TCGA cell cohorts, SLC39A11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,888 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC39A11-associated GO terms across cancer lineages are Copper ion transmembrane transport, Zinc ion import across plasma membrane, and ER-nucleus signaling pathway. Each is linked with SLC39A11 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC39A11-to-partner and partner-to-SLC39A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion transmembrane transport grouped by SLC39A11-low versus SLC39A11-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A11→partner) and Y-score (partner→SLC39A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Copper ion transmembrane transport →	+0.169	+1.061	.001	<.001	3	14
BLOOD_Lymphoma	Zinc ion import across plasma membrane →	+0.128	+1.367	<.001	<.001	3	12
URINARY_TRACT	ER-nucleus signaling pathway →	+0.112	+0.972	.001	<.001	2	13
BONE	Lysosomal lumen acidification →	+0.119	+0.782	<.001	.001	3	12
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.035	+0.962	.001	.001	3	10
URINARY_TRACT	Glycerophospholipid metabolic process →	+0.034	+1.019	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,888 associations by consensus.

Copper ion transmembrane transport by SLC39A11 expression — URINARY_TRACT

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