SLC39A11

Across TCGA cell cohorts, SLC39A11 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC39A11-associated genes across cancer lineages are ODF4, OTUD6A, and SPANXN2. Each is linked with SLC39A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A11-to-partner and partner-to-SLC39A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF4 grouped by SLC39A11-low versus SLC39A11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A11→partner) and Y-score (partner→SLC39A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ODF4 →	+0.124	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OTUD6A →	+0.113	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SPANXN2 →	+0.199	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	LYPD4 →	+0.128	+4.867	<.001	.009	3	1
SKIN	KRT24 →	+0.331	+4.684	<.001	.002	3	1
SKIN	GUCA2B →	+0.116	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

ODF4 by SLC39A11 expression — BLOOD_Lymphoma

Explore this box plot interactively →