SLC38A9

Across TCGA patient cohorts, SLC38A9 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A9-associated genes across cancer lineages are 4E-BP1, ACC1, and HER3_pY1289. Each is linked with SLC38A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A9-to-partner and partner-to-SLC38A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by SLC38A9-low versus SLC38A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A9→partner) and Y-score (partner→SLC38A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.403	+3.459	<.001	.005	3	2
UCEC	ACC1 →	+0.395	+1.584	.005	.036	3	1
UCEC	HER3_pY1289 →	+0.078	+2.999	.021	.035	3	1
UCEC	JNK2 →	+0.206	+2.000	.008	.010	3	1
UCEC	Ku80 →	+0.230	+1.750	.013	.049	3	1
UCEC	MEK1 →	+0.310	+2.000	.031	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

4E-BP1 by SLC38A9 expression — UCEC

Explore this box plot interactively →