SLC38A7

Across TCGA cell cohorts, SLC38A7 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SLC38A7-associated genes across cancer lineages are TAAR5, TRPC3, and ECE2. Each is linked with SLC38A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A7-to-partner and partner-to-SLC38A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR5 grouped by SLC38A7-low versus SLC38A7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A7→partner) and Y-score (partner→SLC38A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAAR5 →	+0.011	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TRPC3 →	+0.553	+4.013	<.001	.001	3	1
LARGE_INTESTINE	ECE2 →	+0.280	+4.376	<.001	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	MMD2 →	+0.036	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	UTF1 →	+0.226	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	USP17L22 →	+0.013	+5.357	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

TAAR5 by SLC38A7 expression — LARGE_INTESTINE

Explore this box plot interactively →