SLC38A7

Across TCGA cell cohorts, SLC38A7 mutation is significantly associated with the mutation status of many other genes, with 1,805 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC38A7-associated genes across cancer lineages are PUM1, ABCA10, and CACNA1D. Each is linked with SLC38A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A7-to-partner and partner-to-SLC38A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PUM1 grouped by SLC38A7-low versus SLC38A7-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A7→partner) and Y-score (partner→SLC38A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PUM1 →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	ABCA10 →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	CACNA1D →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	FAM189B →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	FBLN2 →	+5.392	+5.392	.004	.004	1	3
BLOOD_Leukemia	ZFYVE19 →	+4.560	+4.309	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,805 associations by consensus.

PUM1 by SLC38A7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →