SLC38A6

Across TCGA patient cohorts, SLC38A6 mutation is significantly associated with the RNA expression of many other genes, with 1,707 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A6-associated genes across cancer lineages are MIR4535, BRD1, and ZBED4. Each is linked with SLC38A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A6-to-partner and partner-to-SLC38A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4535 grouped by SLC38A6-low versus SLC38A6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A6→partner) and Y-score (partner→SLC38A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR4535 →	+0.551	+7.741	<.001	.009	3	2
UCEC	BRD1 →	+0.427	+2.923	.008	<.001	3	2
UCEC	ZBED4 →	+0.547	+2.233	.001	.005	3	2
UCEC	PRORP →	+0.373	+2.010	<.001	.006	3	2
UCEC	RBBP8 →	+0.661	+3.601	.003	.001	3	2
UCEC	PARD6A →	+0.822	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,707 associations by consensus.

MIR4535 by SLC38A6 expression — COAD

Explore this box plot interactively →