SLC38A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC38A2 mutation is significantly associated with the RNA expression of many other genes, with 2,102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A2-associated genes across cancer lineages are RNU4-79P, MLLT10P2, and LINC01499. Each is linked with SLC38A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A2-to-partner and partner-to-SLC38A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-79P grouped by SLC38A2-low versus SLC38A2-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A2→partner) and Y-score (partner→SLC38A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADRNU4-79P →+0.213+7.939<.001.00833
CESCMLLT10P2 →+0.114+4.669<.001.00732
CESCLINC01499 →+0.030+4.812<.001.00632
CESCHNRNPA3P16 →+0.050+4.705<.001.00332
LIHCLINC01072 →+0.139+5.305<.001.00332
UCECHAUS1 →+0.420+1.684.007.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,102 associations by consensus.

RNU4-79P by SLC38A2 expression — PRAD

Box plot of RNU4-79P in SLC38A2-low vs SLC38A2-high samples in PRAD.

Explore this box plot interactively →

Exploration