SLC38A2

Across TCGA patient cohorts, SLC38A2 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A2-associated genes across cancer lineages are A-Raf_pS299, JNK_pT183_Y185, and Ku80. Each is linked with SLC38A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A2-to-partner and partner-to-SLC38A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by SLC38A2-low versus SLC38A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A2→partner) and Y-score (partner→SLC38A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.095	-3.700	.038	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.179	-2.571	.005	.001	3	1
UCEC	Ku80 →	+0.207	+1.691	.022	.014	3	1
UCEC	MSH2 →	-0.298	-3.433	<.001	.005	3	1
UCEC	MSH6 →	-0.322	-3.321	.011	.009	3	1
UCEC	NF-kB-p65_pS536 →	-0.413	-3.169	.017	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

A-Raf_pS299 by SLC38A2 expression — UCEC

Explore this box plot interactively →