SLC38A2

Across TCGA cell cohorts, SLC38A2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC38A2-associated genes across cancer lineages are GAPDHS, AGRP, and SLC35G3. Each is linked with SLC38A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A2-to-partner and partner-to-SLC38A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDHS grouped by SLC38A2-low versus SLC38A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A2→partner) and Y-score (partner→SLC38A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GAPDHS →	+0.044	+2.889	.006	.005	3	1
LARGE_INTESTINE	AGRP →	+0.090	+2.672	.001	.004	3	1
LARGE_INTESTINE	SLC35G3 →	+0.005	+2.560	<.001	.008	3	1
LARGE_INTESTINE	CCER1 →	+0.007	+2.977	<.001	.006	3	1
LARGE_INTESTINE	FAM153CP →	+0.234	+3.369	.004	.005	3	1
LARGE_INTESTINE	TECRL →	+0.009	+2.977	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GAPDHS by SLC38A2 expression — LARGE_INTESTINE

Explore this box plot interactively →