SLC38A11

Across TCGA patient cohorts, SLC38A11 mutation is significantly associated with the RNA expression of many other genes, with 1,663 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A11-associated genes across cancer lineages are CCL5, CCL18, and RNA5SP502. Each is linked with SLC38A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A11-to-partner and partner-to-SLC38A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL5 grouped by SLC38A11-low versus SLC38A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A11→partner) and Y-score (partner→SLC38A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL5 →	+1.351	+3.108	<.001	<.001	3	2
UCEC	CCL18 →	+1.306	+2.593	.003	.006	3	2
UCEC	RNA5SP502 →	+0.679	+2.534	<.001	<.001	3	2
UCEC	ALDOA →	+0.512	+3.087	.004	<.001	3	2
UCEC	CD8A →	+1.217	+4.191	<.001	<.001	3	2
UCEC	CXCL13 →	+2.186	+4.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,663 associations by consensus.

CCL5 by SLC38A11 expression — UCEC

Explore this box plot interactively →