SLC37A4

Across TCGA pan-cancer cohorts, SLC37A4 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC37A4 data layer compared with 28 for mass-spec protein and 8 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC37A4 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC37A4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

LUAD, SKCM, and UCEC are the cancer types where SLC37A4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.036	0.791	<.001	18	view →
SKCM	DFS	Median	All	0.087	0.757	<.001	12	view →
UCEC	DFS	Median	All	1.000	0.628	.022	8	view →
PRAD	DFS	Median	All	0.617	0.886	.013	6	view →
STAD	DFS	Median	IV	1.000	0.284	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC37A4–LUAD (DFS)

Open the LUAD breakdown →