SLC37A3

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC37A3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC37A3 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC37A3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC37A3 expression acts as an unfavorable survival marker.

CCRCC, LUAD, and LSCC are the cancer types where SLC37A3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianII,III,IV0.1320.985.03818view →
LUADDFSMedianAll0.5560.944.01711view →
LSCCDFSMedianAll0.8481.000.0491view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC37A3–CCRCC (OS)

Kaplan–Meier survival curve for SLC37A3 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration