SLC37A3

Across TCGA cell cohorts, SLC37A3 mutation is significantly associated with the mutation status of many other genes, with 92 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC37A3-associated genes across cancer lineages are ZYX, ADCY9, and CAPN2. Each is linked with SLC37A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC37A3-to-partner and partner-to-SLC37A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZYX grouped by SLC37A3-low versus SLC37A3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A3→partner) and Y-score (partner→SLC37A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZYX →	+6.044	+6.044	.001	.001	1	1
CNS	ADCY9 →	+4.459	+5.277	.005	.005	1	1
CNS	CAPN2 →	+5.044	+5.614	.003	.003	1	1
CNS	GPR155 →	+5.044	+5.614	.003	.003	1	1
CNS	WDR43 →	+4.459	+5.277	.005	.005	1	1
CNS	CDCP1 →	+4.459	+5.277	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

ZYX by SLC37A3 expression — CNS

Explore this box plot interactively →