Across TCGA pan-cancer cohorts, SLC37A2 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SLC37A2’s most consistent transcriptional readouts.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where SLC37A2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLC37A2 is over-expressed in tumor.
CCRCC and LUAD are the cancer types where SLC37A2 tumor–normal differential expression is most reproducible.