SLC37A2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC37A2 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC37A2-associated genes across cancer lineages are TFRC, Annexin-1, and ATM. Each is linked with SLC37A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC37A2-to-partner and partner-to-SLC37A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SLC37A2-low versus SLC37A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A2→partner) and Y-score (partner→SLC37A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTFRC →+0.704+3.392<.001<.00133
UCECAnnexin-1 →+0.558+2.135.003.01032
UCECATM →-0.577-3.392<.001<.00132
UCEC4E-BP1 →+0.320+3.584.001.00232
UCECEGFR_pY1068 →-0.214-1.700.020.04031
UCECA-Raf_pS299 →-0.142-2.700.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

TFRC by SLC37A2 expression — UCEC

Box plot of TFRC in SLC37A2-low vs SLC37A2-high samples in UCEC.

Explore this box plot interactively →

Exploration