SLC37A2

Across TCGA cell cohorts, SLC37A2 mutation is significantly associated with the RNA expression of many other genes, with 653 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC37A2-associated genes across cancer lineages are TNRC6B, SGSM3, and L3MBTL2. Each is linked with SLC37A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC37A2-to-partner and partner-to-SLC37A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNRC6B grouped by SLC37A2-low versus SLC37A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A2→partner) and Y-score (partner→SLC37A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNRC6B →	+0.768	+3.212	.001	.006	3	1
LARGE_INTESTINE	SGSM3 →	+0.777	+3.212	.001	.006	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.653	+3.212	.001	.006	3	1
LARGE_INTESTINE	CCDC113 →	+0.886	+3.299	.002	.004	3	1
LARGE_INTESTINE	CLUAP1 →	+0.643	+3.385	.004	.004	3	1
LARGE_INTESTINE	PDE4C →	+0.743	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 653 associations by consensus.

TNRC6B by SLC37A2 expression — LARGE_INTESTINE

Explore this box plot interactively →