SLC37A1

Across TCGA pan-cancer cohorts, SLC37A1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC37A1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC37A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC37A1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LSCC, LUAD, and PDAC are the cancer types where SLC37A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.586	0.930	<.001	38	view →
LUAD	DFS	Median	All	0.442	0.896	<.001	18	view →
PDAC	OS	Median	III,IV	0.782	0.338	.011	15	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC37A1–LSCC (OS)

Open the LSCC breakdown →