SLC37A1

Across TCGA patient cohorts, SLC37A1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC37A1-associated genes across cancer lineages are ATM, Caspase-8, and ERK2. Each is linked with SLC37A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC37A1-to-partner and partner-to-SLC37A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC37A1-low versus SLC37A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A1→partner) and Y-score (partner→SLC37A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.521	-1.678	.002	.023	3	2
UCEC	Caspase-8 →	-0.255	-2.087	.008	.005	3	2
UCEC	ERK2 →	+0.167	+2.807	.023	.003	3	1
UCEC	MEK1 →	+0.311	+1.678	.026	.023	3	1
UCEC	MSH2 →	-0.317	-3.558	<.001	.002	3	1
UCEC	MSH6 →	-0.350	-1.678	.005	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ATM by SLC37A1 expression — UCEC

Explore this box plot interactively →