Across TCGA patient cohorts, SLC36A3 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC36A3-associated genes across cancer lineages are MEK1, p62 Lck ligand, and PDCD4. Each is linked with SLC36A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC36A3-to-partner and partner-to-SLC36A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A3→partner) and Y-score (partner→SLC36A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.402	+3.807	.002	<.001	3	2
UCEC	p62 Lck ligand →	+0.293	+1.884	.014	.030	3	2
UCEC	PDCD4 →	-0.533	-1.797	.002	.025	3	2
UCEC	cIAP →	+0.114	+1.594	.024	.042	3	2
UCEC	4E-BP1 →	+0.261	+2.029	.008	.017	3	2
UCEC	Di-Ras3 →	-0.112	-3.446	.039	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

SLC36A3 survival (RNA) · tumor vs normal (RNA) · all SLC36A3 data types