SLC36A2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC36A2 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC36A2-associated genes across cancer lineages are Notch1, p62 Lck ligand, and TFRC. Each is linked with SLC36A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC36A2-to-partner and partner-to-SLC36A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A2→partner) and Y-score (partner→SLC36A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.149+2.472.004.01032
UCECp62 Lck ligand →+0.341+3.584.005.00232
UCECTFRC →+0.479+3.169.016.01832
UCECTuberin_pT1462 →+0.197+1.710.022.02532
UCECATM →-0.507-1.765.002.01432
UCECDi-Ras3 →-0.134-1.765.016.01432
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration