SLC36A1

Across TCGA pan-cancer cohorts, SLC36A1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SLC36A1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLC36A1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types SLC36A1 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD, HNSC, and LUAD are the cancer types where SLC36A1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC36A1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.310	.001	4	view →
HNSC	All	All	+0.291	.037	4	view →
LUAD	Female	All	+0.352	.008	3	view →
LSCC	Female	All	+0.412	.014	2	view →
PDAC	All	All	+0.279	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

SLC36A1–COAD

Open the COAD breakdown →