SLC36A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC36A1 mutation is significantly associated with the RNA expression of many other genes, with 2,491 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC36A1-associated genes across cancer lineages are SLC25A15P1, RNA5SP419, and RNA5SP413. Each is linked with SLC36A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC36A1-to-partner and partner-to-SLC36A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A15P1 grouped by SLC36A1-low versus SLC36A1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A1→partner) and Y-score (partner→SLC36A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCASLC25A15P1 →+0.315+5.497<.001.00433
LUSCRNA5SP419 →+0.822+5.517<.001.00133
LUSCRNA5SP413 →+1.527+5.666<.001<.00133
LUSCRNA5SP415 →+0.863+5.148<.001.00233
STADLINC02509 →+0.091+5.274.001.00633
LGGRN7SL379P →+0.139+7.977<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,491 associations by consensus.

SLC25A15P1 by SLC36A1 expression — BLCA

Box plot of SLC25A15P1 in SLC36A1-low vs SLC36A1-high samples in BLCA.

Explore this box plot interactively →

Exploration