SLC36A1

Across TCGA patient cohorts, SLC36A1 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC36A1-associated genes across cancer lineages are p27_pT198, eIF4E, and PDCD4. Each is linked with SLC36A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC36A1-to-partner and partner-to-SLC36A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT198 grouped by SLC36A1-low versus SLC36A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A1→partner) and Y-score (partner→SLC36A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.087	+2.321	.016	.005	3	3
UCEC	eIF4E →	+0.141	+2.183	.049	.033	3	2
UCEC	PDCD4 →	-0.559	-2.160	<.001	.003	3	2
UCEC	Rad50 →	-0.196	-1.247	.017	.045	3	2
UCEC	Shc_pY317 →	-0.112	-2.000	.030	.029	3	2
UCEC	STAT3_pY705 →	-0.251	-1.574	.004	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

p27_pT198 by SLC36A1 expression — UCEC

Explore this box plot interactively →