SLC36A1

Across TCGA cell cohorts, SLC36A1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC36A1-associated genes across cancer lineages are MAGEB4, RETN, and GH2. Each is linked with SLC36A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC36A1-to-partner and partner-to-SLC36A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by SLC36A1-low versus SLC36A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A1→partner) and Y-score (partner→SLC36A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	3
LUNG_NSCLC_LUAD	RETN →	+0.110	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	GH2 →	+0.066	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	CYP11B1 →	+0.011	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	C9orf92 →	+0.151	+4.212	.002	.007	3	1
LUNG_NSCLC_LUAD	KLRF2 →	+0.053	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MAGEB4 by SLC36A1 expression — LARGE_INTESTINE

Explore this box plot interactively →