SLC35G3

Across TCGA patient cohorts, SLC35G3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G3-associated genes across cancer lineages are Rictor_pT1135, JNK_pT183_Y185, and Annexin-1. Each is linked with SLC35G3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35G3-to-partner and partner-to-SLC35G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by SLC35G3-low versus SLC35G3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G3→partner) and Y-score (partner→SLC35G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rictor_pT1135 →	-0.100	-2.000	.005	.003	3	3
UCEC	JNK_pT183_Y185 →	-0.172	-3.459	.003	.005	3	2
UCEC	Annexin-1 →	+0.461	+3.604	.013	.001	3	2
UCEC	AR →	-0.306	-2.459	.020	.018	3	2
UCEC	TFRC →	+0.565	+2.807	.002	.003	3	2
UCEC	TIGAR →	+0.108	+2.115	.044	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Rictor_pT1135 by SLC35G3 expression — UCEC

Explore this box plot interactively →