SLC35G3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35G3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC35G3-associated genes across cancer lineages are ADRA1A, G6PC2, and CARTPT. Each is linked with SLC35G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G3-to-partner and partner-to-SLC35G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADRA1A grouped by SLC35G3-low versus SLC35G3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G3→partner) and Y-score (partner→SLC35G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEADRA1A →+0.218+4.273<.001.00631
LUNG_NSCLC_LUADG6PC2 →+0.029+4.415<.001<.00131
LUNG_NSCLC_LUADCARTPT →+0.011+4.266<.001.00431
LUNG_NSCLC_LUADIQCF6 →+0.070+3.362<.001.00731
LUNG_NSCLC_LUADCD300H →+0.241+3.882<.001.00331
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ADRA1A by SLC35G3 expression — LARGE_INTESTINE

Box plot of ADRA1A in SLC35G3-low vs SLC35G3-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration