SLC35G2

Across TCGA patient cohorts, SLC35G2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G2-associated genes across cancer lineages are ATM, 14-3-3_beta, and JNK2. Each is linked with SLC35G2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35G2-to-partner and partner-to-SLC35G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC35G2-low versus SLC35G2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G2→partner) and Y-score (partner→SLC35G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.581	-3.169	.003	.019	3	3
UCEC	14-3-3_beta →	-0.088	-3.143	.046	.018	3	1
UCEC	JNK2 →	+0.257	+2.331	.003	.019	3	1
UCEC	MEK1 →	+0.410	+2.115	.010	.019	3	1
UCEC	MSH2 →	-0.360	-2.807	<.001	.003	3	1
UCEC	Notch1 →	+0.199	+2.335	.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

ATM by SLC35G2 expression — UCEC

Explore this box plot interactively →