SLC35G2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35G2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35G2-associated genes across cancer lineages are PRLHR, FAM71C, and SCYGR10. Each is linked with SLC35G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G2-to-partner and partner-to-SLC35G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRLHR grouped by SLC35G2-low versus SLC35G2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G2→partner) and Y-score (partner→SLC35G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPRLHR →+0.023+5.201<.001.00631
SKINFAM71C →+0.012+4.095.008.00931
SKINSCYGR10 →+0.194+4.684<.001.00231
LARGE_INTESTINETSHB →+0.070+5.000<.001<.00131
LARGE_INTESTINEOR4D1 →+0.005+4.217.006.00131
LARGE_INTESTINECOX6A2 →+0.082+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

PRLHR by SLC35G2 expression — BLOOD_Leukemia

Box plot of PRLHR in SLC35G2-low vs SLC35G2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration