Across TCGA patient cohorts, SLC35F6 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F6-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and Heregulin. Each is linked with SLC35F6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F6-to-partner and partner-to-SLC35F6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F6→partner) and Y-score (partner→SLC35F6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.354	-3.584	.003	.002	3	1
UCEC	eIF4E →	+0.243	+2.459	.017	.020	3	1
UCEC	Heregulin →	-0.206	-3.321	<.001	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.243	-2.459	.002	.019	3	1
UCEC	Ku80 →	+0.343	+3.009	.002	.019	3	1
UCEC	MEK1 →	+0.525	+3.584	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

SLC35F6 survival (RNA) · tumor vs normal (RNA) · all SLC35F6 data types