SLC35F5

Across TCGA pan-cancer cohorts, SLC35F5 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC35F5 data layer compared with 28 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC35F5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC35F5 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRC, KIRP, and BRCA are the cancer types where SLC35F5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.150	0.806	<.001	42	view →
KIRP	OS	Median	All	0.571	0.903	<.001	36	view →
BRCA	OS	Median	III,IV	0.313	0.834	.004	20	view →
UCEC	DFS	Median	All	1.000	0.622	.020	10	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC35F5–KIRC (OS)

Open the KIRC breakdown →