SLC35F5

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC35F5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC35F5 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC35F5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35F5 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

LUAD, PDAC, and UCEC are the cancer types where SLC35F5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.5471.000.00920view →
PDACDFSQuartileAll0.5700.850.00418view →
UCECDFSTertileII,III,IV0.9430.360.0248view →
LSCCOSMedianIII,IV0.4730.873.0316view →
GBMDFSTertileAll0.8040.413.0243view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC35F5–LUAD (DFS)

Kaplan–Meier survival curve for SLC35F5 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration