SLC35F5

Across TCGA patient cohorts, SLC35F5 mutation is significantly associated with the RNA expression of many other genes, with 917 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F5-associated genes across cancer lineages are NKX2-6, TSEN15P3, and MIR4510. Each is linked with SLC35F5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F5-to-partner and partner-to-SLC35F5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKX2-6 grouped by SLC35F5-low versus SLC35F5-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F5→partner) and Y-score (partner→SLC35F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	NKX2-6 →	+0.063	+5.679	<.001	.003	3	2
BRCA	TSEN15P3 →	+0.163	+8.055	<.001	.007	3	2
CESC	MIR4510 →	+0.403	+6.342	<.001	.001	3	2
LUAD	ACER2P1 →	+0.121	+4.609	<.001	.001	3	2
LUAD	IQCF5 →	+0.102	+5.000	<.001	.003	3	2
LUAD	MIR3667 →	+0.522	+3.722	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 917 associations by consensus.

NKX2-6 by SLC35F5 expression — LGG

Explore this box plot interactively →