SLC35F5

Across TCGA patient cohorts, SLC35F5 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F5-associated genes across cancer lineages are eEF2, ERK2, and p70-S6K_pT389. Each is linked with SLC35F5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F5-to-partner and partner-to-SLC35F5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SLC35F5-low versus SLC35F5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F5→partner) and Y-score (partner→SLC35F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.436	+1.700	.004	.044	3	2
UCEC	ERK2 →	+0.254	+3.169	.001	.018	3	2
UCEC	p70-S6K_pT389 →	-0.229	-1.700	.004	.044	3	2
UCEC	PDCD4 →	-0.559	-1.700	.005	.044	3	2
UCEC	Rictor_pT1135 →	-0.136	-2.906	.001	.001	3	2
UCEC	ATM →	-0.583	-2.906	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

eEF2 by SLC35F5 expression — UCEC

Explore this box plot interactively →