SLC35F5

Across TCGA cell cohorts, SLC35F5 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC35F5-associated genes across cancer lineages are TBC1D21, SPINK9, and C4orf50. Each is linked with SLC35F5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F5-to-partner and partner-to-SLC35F5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by SLC35F5-low versus SLC35F5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F5→partner) and Y-score (partner→SLC35F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SPINK9 →	+0.323	+3.793	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	C4orf50 →	+0.013	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	TRIM77 →	+0.030	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	SKOR2 →	+0.022	+4.736	<.001	.009	3	1
CNS	TEX43 →	+0.201	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TBC1D21 by SLC35F5 expression — LARGE_INTESTINE

Explore this box plot interactively →