SLC35F3

Across TCGA patient cohorts, SLC35F3 mutation is significantly associated with the RNA expression of many other genes, with 1,407 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F3-associated genes across cancer lineages are PANK4, CHAF1B, and FANCA. Each is linked with SLC35F3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35F3-to-partner and partner-to-SLC35F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PANK4 grouped by SLC35F3-low versus SLC35F3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F3→partner) and Y-score (partner→SLC35F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PANK4 →	+0.322	+2.969	<.001	<.001	3	3
SKCM	CHAF1B →	+0.372	+1.505	.006	.003	3	3
UCEC	FANCA →	+0.587	+3.021	<.001	<.001	3	3
UCEC	ZMYND19 →	+0.300	+1.546	.009	.009	3	3
UCEC	NCAPH2 →	+0.527	+2.523	<.001	<.001	3	3
COAD	ZFYVE19 →	+0.491	+3.459	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,407 associations by consensus.

PANK4 by SLC35F3 expression — SKCM

Explore this box plot interactively →