SLC35F3

Across TCGA patient cohorts, SLC35F3 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F3-associated genes across cancer lineages are PCNA, MEK1, and PDCD4. Each is linked with SLC35F3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35F3-to-partner and partner-to-SLC35F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC35F3-low versus SLC35F3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F3→partner) and Y-score (partner→SLC35F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.209	+1.765	.009	.014	3	3
UCEC	MEK1 →	+0.408	+2.700	.002	.006	3	2
UCEC	PDCD4 →	-0.519	-2.000	.003	.029	3	2
UCEC	ATM →	-0.617	-2.906	<.001	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.575	+1.604	.009	.041	3	2
UCEC	Chk2 →	-0.214	-2.459	.015	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

PCNA by SLC35F3 expression — UCEC

Explore this box plot interactively →