SLC35F3

Across TCGA cell cohorts, SLC35F3 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35F3-associated genes across cancer lineages are HAND1, PLXDC2, and GDF6. Each is linked with SLC35F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F3-to-partner and partner-to-SLC35F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAND1 grouped by SLC35F3-low versus SLC35F3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F3→partner) and Y-score (partner→SLC35F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HAND1 →	+0.102	+3.884	.002	.001	3	1
SKIN	PLXDC2 →	+0.995	+3.385	<.001	.004	3	1
SKIN	GDF6 →	+1.229	+3.201	<.001	.009	3	1
SKIN	FAM111A →	+0.703	+3.299	.003	.004	3	1
SKIN	PRKCE →	+0.725	+3.212	.006	.006	3	1
SKIN	OR10H5 →	+0.010	+3.392	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

HAND1 by SLC35F3 expression — SKIN

Explore this box plot interactively →