SLC35F3-AS1

Across TCGA pan-cancer cohorts, SLC35F3-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SLC35F3-AS1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher SLC35F3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35F3-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

DLBC, ESCA, and LUSC are the cancer types where SLC35F3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	II,III,IV	0.357	0.875	.001	42	view →
ESCA	OS	Median	III,IV	0.711	0.442	.005	39	view →
LUSC	OS	Tertile	III,IV	0.498	0.724	.005	27	view →
PCPG	DFS	Tertile	All	0.485	0.871	.002	24	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	24	view →
OV	DFS	Tertile	IV	0.293	0.509	.017	20	view →
THCA	DFS	Tertile	III,IV	0.662	0.836	.029	18	view →
KICH	DFS	Tertile	IV	0.317	0.923	.038	9	view →
MESO	OS	Tertile	II,III,IV	0.306	0.577	.042	9	view →
PAAD	DFS	Tertile	All	0.454	0.238	.016	9	view →
SKCM	OS	Tertile	III,IV	0.173	0.698	.002	9	view →
TGCT	DFS	Tertile	All	0.898	0.752	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

SLC35F3-AS1–DLBC (DFS)

Open the DLBC breakdown →