SLC35F2

Across TCGA pan-cancer cohorts, SLC35F2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35F2 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC35F2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC35F2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

LSCC, HNSC, and GBM are the cancer types where SLC35F2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.657	0.843	.022	16	view →
HNSC	OS	Median	All	0.796	0.554	.025	6	view →
GBM	OS	Median	All	0.489	0.281	.010	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC35F2–LSCC (OS)

Open the LSCC breakdown →