SLC35F2

Across TCGA patient cohorts, SLC35F2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F2-associated genes across cancer lineages are Ku80, FOXO3a_pS318_S321, and MAPK_pT202_Y204. Each is linked with SLC35F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F2-to-partner and partner-to-SLC35F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by SLC35F2-low versus SLC35F2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F2→partner) and Y-score (partner→SLC35F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.267	+2.598	.015	.006	3	2
UCEC	FOXO3a_pS318_S321 →	-0.154	-2.449	.008	.019	3	1
UCEC	MAPK_pT202_Y204 →	-0.468	-2.321	.032	.034	3	1
UCEC	Notch1 →	+0.155	+2.820	.018	.035	3	1
UCEC	p62 Lck ligand →	+0.500	+3.700	<.001	.001	3	1
UCEC	p70-S6K →	+0.201	+2.611	.025	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Ku80 by SLC35F2 expression — UCEC

Explore this box plot interactively →