SLC35F2

Across TCGA cell cohorts, SLC35F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,538 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC35F2-associated GO terms across cancer lineages are tRNA wobble guanine modification, Pyruvate decarboxylation to acetyl-CoA, and Transcription initiation at RNA polymerase I promoter. Each is linked with SLC35F2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLC35F2-to-partner and partner-to-SLC35F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble guanine modification grouped by SLC35F2-low versus SLC35F2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F2→partner) and Y-score (partner→SLC35F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA wobble guanine modification →	+0.216	+1.881	<.001	<.001	3	16
OESOPHAGUS	Pyruvate decarboxylation to acetyl-CoA →	+0.139	+1.198	<.001	.002	3	11
BONE	Transcription initiation at RNA polymerase I promoter →	+0.103	+1.928	.001	<.001	3	11
BONE	Mitochondrial tRNA pseudouridine synthesis →	+0.156	+2.141	<.001	<.001	3	11
CNS	tRNA wobble base modification →	+0.077	+1.478	<.001	<.001	3	11
BREAST	Pyruvate catabolic process →	+0.304	+2.102	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,538 associations by consensus.

tRNA wobble guanine modification by SLC35F2 expression — BONE

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