SLC35F1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35F1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F1-associated genes across cancer lineages are mTOR_pS2448, ASNS, and PAI-1. Each is linked with SLC35F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35F1-to-partner and partner-to-SLC35F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F1→partner) and Y-score (partner→SLC35F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADmTOR_pS2448 →-0.266-3.000.011.03633
LUADASNS →+0.620+3.000.015.03633
LUADPAI-1 →+1.110+3.000.003.03532
LUADPDCD4 →-0.799-2.983<.001.03632
LUADStathmin →+0.225+3.000.016.03632
LUADTransglutaminase →-0.361-3.000.048.03532
Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration