SLC35E3

Across TCGA patient cohorts, SLC35E3 protein abundance is significantly associated with the RNA expression of many other genes, with 438 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC35E3-associated genes across cancer lineages are COMT, COL1A1, and ARHGEF17. Each is linked with SLC35E3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35E3-to-partner and partner-to-SLC35E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC35E3 versus COMT in GBM, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E3→partner) and Y-score (partner→SLC35E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COMT →	-0.544	-0.705	.001	.004	3	2
HNSC	COL1A1 →	+2.626	+1.138	<.001	.009	3	1
HNSC	ARHGEF17 →	+1.048	+1.134	.003	.009	3	1
HNSC	TOX2 →	+1.107	+1.492	.005	.005	3	1
HNSC	COL5A1 →	+2.087	+1.135	.003	.009	3	1
HNSC	PRICKLE1 →	+1.858	+1.449	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 438 associations by consensus.

SLC35E3 vs COMT — GBM

Explore this scatter interactively →