SLC35E3

Across TCGA patient cohorts, SLC35E3 mutation is significantly associated with the RNA expression of many other genes, with 505 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35E3-associated genes across cancer lineages are LINC01995, SRIP2, and SERPINH1. Each is linked with SLC35E3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35E3-to-partner and partner-to-SLC35E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01995 grouped by SLC35E3-low versus SLC35E3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E3→partner) and Y-score (partner→SLC35E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01995 →	+0.336	+6.003	<.001	.002	3	2
LUSC	SRIP2 →	+0.194	+5.337	.003	.006	3	2
UCEC	SERPINH1 →	+0.736	+3.332	.001	.005	3	1
UCEC	MTA2 →	+0.567	+3.212	<.001	.009	3	1
UCEC	KCTD14 →	+1.314	+3.617	<.001	.001	3	1
UCEC	CCDC3 →	-0.949	-3.584	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 505 associations by consensus.

LINC01995 by SLC35E3 expression — COAD

Explore this box plot interactively →