SLC35E3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35E3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,391 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35E3-associated GO terms across cancer lineages are Microtubule polymerization, mRNA alternative polyadenylation, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with SLC35E3 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC35E3-to-partner and partner-to-SLC35E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by SLC35E3-low versus SLC35E3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E3→partner) and Y-score (partner→SLC35E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaMicrotubule polymerization →+0.075+1.082<.001<.001312
BONEmRNA alternative polyadenylation →+0.080+0.813.002<.001310
UPPER_AERODIGESTIVE_TRACTPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.170+0.843<.001.001310
LUNG_NSCLC_LUADCytoskeleton-dependent cytokinesis →+0.049+0.749.001<.00139
BLOOD_LymphomaRegulation of DNA-templated transcription initiation →+0.050+1.006<.001<.00139
BLOOD_LymphomaInterstrand cross-link repair →+0.048+0.825.001.00239
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,391 associations by consensus.

Microtubule polymerization by SLC35E3 expression — BLOOD_Leukemia

Box plot of Microtubule polymerization in SLC35E3-low vs SLC35E3-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration